C5AR1 Polyclonal Antibody

SKU: E-AB-18573

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: C5AR1

Target Synonym: ANAPHYLATOXIN RECEPTOR;C5a anaphylatoxin chemotactic receptor;C5a anaphylatoxin receptor;C5A;C5a ligand;C5a-R;C5aR;C5AR;c5ar1;C5R1;CD88;CD88 antigen;Complement component 5 receptor 1;Complement component 5 receptor 2;Complement component 5a receptor 1

Research Areas: Cancer;Metabolism;Immunology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P21730

Accession:

Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).

Concentration: 0.7 mg/mL

Immunogen: Fusion protein of human C5AR1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:40-1:200

Calculated MW:

ObservedMW: