C4BPB Polyclonal Antibody

SKU: E-AB-52505

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:C4BPB

Target Synonym:C4b binding protein beta chain;C4b-binding protein beta chain;C4BP;C4BPB;C4BPB;Complement component 4 binding protein beta;Complement component 4 binding protein beta chain;Complement component 4-binding protein beta;OTTHUMP00000034288;OTTHUMP00000034289;OTTHUMP00000034375;OTTHUMP0000003474;Proline rich protein;PRP

Research Areas:Cancer;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P20851

Accession:

Background:This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.

Concentration:0.7 mg/mL

Immunogen:Fusion protein of human C4BPB

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:30-1:150

Calculated MW:

ObservedMW: