C-Kit Monoclonal Antibody

SKU: BT-MCA3136

Size:100μL

Background:C-kit (CD117, 145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

Research_area:Others

Target_protein:C-Kit

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:8D7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:C-Kit

Immunogen:Purified recombinant fragment of C-kit expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):145kDa

UniProt accession:P10721

Synonyms:PBT, SCFR, C-Kit, CD117, KIT

GeneID:3815