Btk(Phospho-Ser180) Rabbit Polyclonal Antibody

SKU: BT-AP06625

Size:100μL

Background:The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1| which is an immunodeficiency characterized by the failure to produce mature B lymphocytes| and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research_area:Immunology; Signal transduction

Target_protein:BTK

applications:WB

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Btk

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q06187; Mouse: P35991

Synonyms:Btk ;Ser180; Tyrosine-protein kinase BTK; EC 2.7.10.2; Agammaglobulinaemia tyrosine kinase; ATK; B-cell progenitor kinase; BPK; Bruton tyrosine kinase

GeneID:Human: 695; Mouse: 12229