BPGM Polyclonal Antibody

SKU: E-AB-18543

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: BPGM

Target Synonym: 2;2;3-bisphosphoglycerate mutase;2;3-bisphosphoglycerate mutase; erythrocyte;2;3-bisphosphoglycerate synthase;2;3-diphosphoglycerate mutase;3-bisphosphoglycerate mutase;3-bisphosphoglycerate synthase;3-diphosphoglycerate mutase;Ab2 098;AI323730;AL022789;Bisphosphoglycerate mutase;BPG dependent PGAM;BPG-dependent PGAM;Bpgm;C86192;DPGM;Erythrocyte 2;3 bisphosphoglycerate mutase;erythrocyte;PMGE

Research Areas: Cancer;Cardiovascular;Metabolism;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P07738

Accession:

Background: 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Concentration: 1.1 mg/mL

Immunogen: Full length fusion protein

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:1000-1:5000;IHC 1:50-1:300

Calculated MW: 30 kDa

ObservedMW: Refer to figures