Bovine dipeptidyl peptidase 4,DPP4 ELISA KIT

SKU: E0034Bo

Size:96Tests

Background:Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline. {ECO:0000250|UniProtKB:P27487}.

Research_area:

Applications:ELISA

Target_protein:DPP4

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:0.26ng/mL

Detection range:0.5-32ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:dipeptidyl peptidase 4

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P81425

MASS(Da):88369

GeneID:281122

Synonyms:DPP4 CD26

Gene names:DPP4

Standard solution:64ng/mL