Beclin-1 mouse Monoclonal Antibody(5C2)

SKU: BT-MCA0210

Size:100μL

Background:This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Research_area:Epigenetics and nuclear signaling; Cancer; Metabolism; Microbiology

Target_protein:BECN1

applications:WB, IHC-p, IF

Reactivity:Human,Rat,Mouse

Clonality:Monoclonal

Clone ID:

Host:Mouse

Isotype:IgG

Gene Symbol/ Name:BECN1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):N/A

UniProt accession:Human: Q14457; Mouse: O88597; Rat: Q91XJ1

Synonyms:BECN1

GeneID:Human: 8678