BCL2A1 Antibody - Cat. #: CSB-PA561279

SKU: CSB-PA561279

Size :50ul

Clone Number:

Aliases:ACC 1 antibody; ACC 2 antibody; B2LA1_HUMAN antibody; Bcl 2 related protein A1 antibody; Bcl-2-like protein 5 antibody; Bcl-2-related protein A1 antibody; BCL2 related protein A1 antibody; Bcl2-L-5 antibody; BCL2A1 antibody; BCL2L5 antibody; BFL1 antibody; GRS antibody; HBPA1 antibody; Hematopoietic BCL2 related protein A1 antibody; Hemopoietic specific early response protein antibody; Hemopoietic-specific early response protein antibody; Protein BFL 1 antibody; Protein BFL-1 antibody; Protein GRS antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q16548

Immunogen:Fusion protein of Human BCL2A1

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100

Background:This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:BCL2A1

Research Areas:Cell biology