BBC3 Polyclonal Antibody

SKU: E-AB-40332

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: BBC3

Target Synonym: BBC 3;Bbc3;BBC3;BCL 2 binding component 3;Bcl-2-binding component 3;BCL2 binding component 3;JFY 1;JFY-1;JFY1;p53 up regulated modulator of apoptosis;p53 up-regulated modulator of apoptosis;p53 Upregulated Modulator of Apoptosis;PUMA alpha;PUMA/JFY1

Research Areas: Cancer;Cell Biology;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9BXH1

Accession:

Background: This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

Concentration: 1 mg/mL

Immunogen: Recombinant Human Bcl-2-binding component 3 protein

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: WB 1:500-1000;IHC 1:100-1:200

Calculated MW: 21kDa

ObservedMW: 26kDa