BACE2 Polyclonal Antibody

SKU: BT-AP06647

Size:100μL

Background:This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.

Research_area:Cell biology; Neuroscience

Target_protein:BACE2

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Beta-secretase 2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q9Y5Z0; Mouse: Q9JL18; Rat: Q6IE75

Synonyms:Beta-secretase 2 ;EC 3.4.23.45;Aspartic-like protease 56 kDa;Aspartyl protease 1;ASP1;Asp 1;Beta-site amyloid precursor protein cleaving enzyme 2;Beta-site APP cleaving enzyme 2;Down reg

GeneID:Human: 25825