B7-H3/CD276 Monoclonal Antibody

SKU: AN200023P

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:CD276

Target Synonym:B7H;UNQ;PRO;B7-H;B7RP;B7 homolog;B7H34Ig-B7-H;PSEC;4Ig-B7-H;CD276;4Ig-B7-H3;B7-H3;B7H3;B7RP-2;B7 homolog 3;B7H34Ig-B7-H3;CD276 antigen;CD276 molecule;Costimulatory molecule;PSEC0249;UNQ309;PRO352;B7RP-2;4Ig-B7-H3;B7H3;B7-H3;CD276 antigen

Research Areas:Immunology;Cancer;Stem Cells

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM;ICC/IF

Isotype:IgG2b

Clonality:Monoclonal

Clone NO.:1F13

UNIProt ID:Q5ZPR3

Accession:

Background:The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration:1 mg/mL

Immunogen:Recombinant Human B7-H3 / CD276 protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:ICC/IF 1:50-1:1000;FCM 1:25-1:100;

Calculated MW:

ObservedMW: