B4GAT1 Antibody, FITC conjugated - Cat. #: CSB-PA002499EC01HU

SKU: CSB-PA002499EC01HU

Size :50ug

Clone Number:

Aliases:3-N-acetylglucosaminyltransferase 1 antibody; 3-N-acetylglucosaminyltransferase antibody; B3GN-T1 antibody; B3GN1_HUMAN antibody; B3GNT1 antibody; B3GNT6 antibody; beta-1,3-N-acetylglucosaminyltransferase bGnT-6 antibody; BETA3GNTI antibody; I-beta-1 antibody; i-beta-1,3-N-acetylglucosaminyltransferase antibody; iGAT antibody; iGnT antibody; N-acetyllactosaminide beta-1 antibody; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase antibody; OTTHUMP00000235058 antibody; Poly-N-acetyllactosamine extension enzyme antibody; UDP-GlcNAc:betaGal beta-1 antibody; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1 antibody; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O43505

Immunogen:Recombinant Human Beta-1,4-glucuronyltransferase 1 protein (161-415AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose-beta disaccharide primer, which is further elongated by LARGE, during synthesis of phosphorylated O-mannosyl glycan (PubMed:25279699, PubMed:25279697). Phosphorylated O-mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:25279699, PubMed:25279697). Required for axon guidance; via its function in O-mannosylation of alpha-dystroglycan (DAG1).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:B4GAT1

Research Areas:Metabolism; Signal transduction