AVP Receptor V3 rabbit pAb

SKU: ES8759

Size: 100μL

Source:Rabbit

Applications:IHC;IF;ELISA

Reactivity:Human;Mouse;Rat

Dilution:IHC-p 1:50-200, ELISA 1:10000-20000

Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human AVPR1B. AA range:271-320

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:553

Human_swiss_prot_no:P47901

Subcellular_location:Cell membrane ; Multi-pass membrane protein .

Other_name:Vasopressin V1b receptor (V1bR;AVPR V1b;AVPR V3;Antidiuretic hormone receptor 1b;Vasopressin V3 receptor)

Background:The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known. [provided by RefSeq, Jul 2008],