ATR Monoclonal Antibody

SKU: BT-MCA2809

Size:100μL

Background:The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:ATR

applications:FCM

Reactivity:

Clonality:Monoclonal

Clone ID:3G6D2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:ATR

Immunogen:Purified recombinant fragment of human ATR (AA: 366-550) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):301kDa

UniProt accession:Q13535

Synonyms:FRP1, MEC1, SCKL, FCTCS, SCKL1

GeneID:545