ATG7 (3D6) Mouse mAb

SKU: EM1385

Size: 100μL

Source:Mouse

Applications:IHC

Reactivity:Human, Mouse, Rat

Dilution:IHC 1:100-200

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):78kDa

Human_gene_id:10533

Human_swiss_prot_no:O95352

Subcellular_location:Cytoplasm

Other_name:APG7, GSA7, Autophagy related protein 7

Background:The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.