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Gene Bio Systems

ATF6 Antibody, Biotin conjugated - Cat. #: CSB-PA002277LD01HU

ATF6 Antibody, Biotin conjugated - Cat. #: CSB-PA002277LD01HU

CSB-PA002277LD01HU

£290.00 GBP
£290.00 GBP
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Size :50ul

Clone Number:

Aliases:Activating transcription factor 6 alpha antibody; Activating transcription factor 6 antibody; ATF 6 antibody; ATF6 alpha antibody; ATF6 antibody; ATF6-alpha antibody; ATF6A antibody; ATF6A_HUMAN antibody; cAMP dependent transcription factor ATF 6 alpha antibody; cAMP-dependent transcription factor ATF-6 alpha antibody; Cyclic AMP dependent transcription factor ATF 6 alpha antibody; DKFZp686P2194 antibody; ESTM49 antibody; FLJ21663 antibody; Processed cyclic AMP dependent transcription factor ATF 6 alpha antibody; Processed cyclic AMP-dependent transcription factor ATF-6 alpha antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P18850

Immunogen:Recombinant Human Cyclic AMP-dependent transcription factor ATF-6 alpha protein (1-194AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5\'-CCAC[GA]-3\'half of the ER stress response element (ERSE) (5\'-CCAAT-N(9)-CCAC[GA]-3\') and of ERSE II (5\'-ATTGG-N-CCACG-3\'). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Antigen Affinity purified & Affinity purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ATF6

Research Areas:Signal Transduction

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