ATF3 Antibody - Cat. #: CSB-PA067046

SKU: CSB-PA067046

Size :100ul

Clone Number:

Aliases:Activating transcription factor 3 antibody; ATF3 antibody; ATF3_HUMAN antibody; ATF3deltaZip2 antibody; ATF3deltaZip2c antibody; ATF3deltaZip3 antibody; cAMP dependent transcription factor ATF3 antibody; cAMP-dependent transcription factor ATF-3 antibody; Cyclic AMP dependent transcription factor ATF3 antibody; Cyclic AMP-dependent transcription factor ATF-3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P18847

Immunogen:Synthesized peptide derived from internal of Human ATF3.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters.

Chen B.P.C., J. Biol. Chem. 269:15819-15826(1994).
Hai T., Genes Dev. 3:2083-2090(1989).
Hillman R.T., Genome Biol. 5:RESEARCH008.1-RESEARCH008.16(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ATF3

Research Areas:Epigenetics and Nuclear Signaling;Cancer