ATF2 Monoclonal Antibody

SKU: BT-MCA2473

Size:100μL

Background:This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:ATF2

applications:WB, IHC

Reactivity:Human, Mouse

Clonality:Monoclonal

Clone ID:4F12

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:ATF2

Immunogen:Purified recombinant fragment of human ATF2 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):55kDa

UniProt accession:P15336

Synonyms:HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2

GeneID:1386