ATAT1 Antibody, HRP conjugated - Cat. #: CSB-PA725542LB01HU

SKU: CSB-PA725542LB01HU

Size :50ug

Clone Number:

Aliases:Acetyltransferase mec 17 homolog antibody; Acetyltransferase mec-17 homolog antibody; Alpha TAT antibody; Alpha tubulin acetyltransferase 1 antibody; Alpha tubulin N acetyltransferase antibody; Alpha-TAT antibody; Alpha-tubulin N-acetyltransferase antibody; ATAT_HUMAN antibody; ATAT1 antibody; Chromosome 6 open reading frame 134 antibody; Hypothetical protein LOC79969 antibody; MEC17 antibody; Nbla00487 antibody; TAT antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q5SQI0

Immunogen:Recombinant Human Alpha-tubulin N-acetyltransferase 1 protein (194-238AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Specifically acetylates \'Lys-40\' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ATAT1

Research Areas:Cell biology