APOC1 Rabbit pAb

SKU: ES18289

Size: 100μL

Source:Rabbit

Applications:IHC; ELISA

Reactivity:Human;Rat;Mouse;

Dilution:IHC-p 1:50-200, ELISA(peptide)1:5000-20000

Immunogen:Synthesized peptide derived from human APOC1 AA range: 1-50

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:341

Human_swiss_prot_no:P02654

Subcellular_location:Secreted .

Other_name:Apolipoprotein C-I (Apo-CIB;ApoC-IB;Apolipoprotein C1) [Cleaved into: Truncated apolipoprotein C-I (Apo-CIB';ApoC-IB')]

Background:This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Sep 2016],