APC Antibody - Cat. #: CSB-PA589353

SKU: CSB-PA589353

Size :50ul

Clone Number:

Aliases:Adenomatous Polyposis Coli antibody; Adenomatous polyposis coli protein antibody; Apc antibody; APC_HUMAN antibody; CC1 antibody; Deleted in polyposis 2.5 antibody; DP2 antibody; DP2.5 antibody; DP3 antibody; FAP antibody; FPC antibody; GS antibody; Protein APC antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P25054

Immunogen:Synthetic peptide of Human APC

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100

Background:This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:APC

Research Areas:Epigenetics and Nuclear Signaling?Neuroscience?Cancer?Cardiovascular?Cell biology;Stem cells