Anti-ZWINT Antibody Picoband®

SKU: A07023

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5μg/ml, Rat
ELISA, 0.1-0.5μg/ml,

Gene Name: Zwint

Specificity:

Background: ZW10 interactor (Zwint-1) is a protein that in humans is encoded by the ZWINT gene. This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived rat ZWINT recombinant protein (Position: M1-D253).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: ZWINT ZW10 interactor. 2. Obuse C, Iwasaki O, Kiyomitsu T, Goshima G, Toyoda Y, Yanagida M (Nov 2004). A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. Nature Cell Biology 6 (11): 1135–41. 3. van Vlijmen T, Vleugel M, Evers M, Mohammed S, Wulf PS, Heck AJ, Hoogenraad CC, van der Sluijs P (Aug 2008). A unique residue in rab3c determines the interaction with novel binding protein Zwint-1. FEBS Letters 582 (19): 2838–42.

Uniprot ID: Q8VIL3

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 38 kDa

Calculated Molecular Weight:

Gene ID: 257644

Protein Name: Outer kinetochore KNL1 complex subunit ZWINT

Gene Full Name: ZW10 interacting kinetochore protein

Synonyms: Zwint; Sip30; ZW10 interactor; SNAP25-interacting protein 30; Scoilin; ZW10-interacting protein 1; Zwint-1