Anti-WRS/WARS1 Antibody Picoband®

SKU: A02444-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse

Applications: WB,IHC,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: WARS1

Specificity:

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.

Immunogen: E.coli-derived human WRS/WARS1 recombinant protein (Position: E5-K369).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Borglum, A. D., Flint, T., Tommerup, N., Fleckner, J., Justesen, J., Kruse, T. A. Assignment of the human tryptophanyl-tRNA synthetase gene (WARS) to chromosome 14q32.2-q32.32. Cytogenet. Cell Genet. 73: 99-103, 1996. 2. Denney, R. M., Borgaonkar, D., Ruddle, F. H. Order of genes for NP and TRPRS on chromosome 14. Cytogenet. Cell Genet. 22: 493-497, 1978. 3. Francke, U., Denney, R. M., Ruddle, F. H. Intrachromosomal gene mapping in man: the gene for tryptophanyl-tRNA synthetase maps in region q21-qter of chromosome 14. Somat. Cell Genet. 3: 381-389, 1977.

Uniprot ID: P23381

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 55 kDa

Calculated Molecular Weight: 38779 MW

Gene ID: 7453

Protein Name: Tryptophan--tRNA ligase, cytoplasmic

Gene Full Name: tryptophanyl-tRNA synthetase 1

Synonyms: GAMMA 2; hWRS; IFI53; IFP53; Interferon induced protein 53; TrpRS; Tryptophan tRNA ligase; Tryptophanyl-tRNA synthetase; WARS; WARS1; WRS