Anti-WNT8B Antibody Picoband®

SKU: A07933-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC,IF,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: WNT8B

Specificity:

Background: Protein Wnt-8b is a protein that in humans is encoded by the WNT8B gene. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear identical and are restricted to the developing brain. The chromosomal location of this gene to 10q24 suggests it as a candidate gene for partial epilepsy.

Immunogen: E.coli-derived human WNT8B recombinant protein (Position: A206-R340).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Houart, C., Caneparo, L., Heisenberg, C.-P., Barth, K. A., Take-Uchi, M., Wilson, S. W. Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling. Neuron 35: 255-265, 2002. 2. Lako, M., Lindsay, S., Bullen, P., Wilson, D. I., Robson, S. C., Strachan, T. A novel mammalian Wnt gene, WNT8B, shows brain-restricted expression in early development, with sharply delimited expression boundaries in the developing forebrain. Hum. Molec. Genet. 7: 813-822, 1998. 3. Lako, M., Strachan, T., Curtis, A. R. J., Lindsay, S. Isolation and characterization of WNT8B, a novel human Wnt gene that maps to 10q24. Genomics 35: 386-388, 1996.

Uniprot ID: Q93098

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 40-50 kDa

Calculated Molecular Weight: 49229 MW

Gene ID: 7479

Protein Name: Protein Wnt-8b

Gene Full Name: Wnt family member 8B

Synonyms: WNT8B; Protein Wnt-8b