Anti-UBE2A/2B Antibody Picoband®

SKU: A05264-2

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: UBE2A/2B

Specificity:

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with cognitive disability. Alternative splicing results in multiple transcript variants.

Immunogen: E.coli-derived human UBE2A/2B recombinant protein (Position: M1-C152). Human UBE2A/2B shares 100% amino acid (aa) sequence identity with mouse UBE2A/2B.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference:

Uniprot ID: P49459|P63146

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 17 kDa

Calculated Molecular Weight: 17 kDa

Gene ID: 7319/7320

Protein Name:

Gene Full Name: ubiquitin conjugating enzyme E2 A/ubiquitin conjugating enzyme E2 B

Synonyms: HHR6A; HR6A; RAD6 homolog A; RAD6A; UBC2; UBE2A; Ubiquitin carrier protein A; Ubiquitin protein ligase A; E2 17kDa; HHR6B; HR6B; RAD6 homolog B; RAD6B; UBC2; UBE2B; Ubiquitin carrier protein B; Ubiquitin protein ligase B