Anti-TSTA3/GFUS Antibody Picoband®

SKU: A09921-3

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.1-0.25 μg/ml, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: GFUS

Specificity:

Background: Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.

Immunogen: E.coli-derived human TSTA3/GFUS recombinant protein (Position: K44-K321).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Lenzerini, L., Benatti, U., Morelli, A., Pontremoli, S., De Flora, A., Piazza, A., Rinaldi, A., Filippi, G., Siniscalco, M. Genetic variation in the quantitative levels of an NADP(H)-binding protein (FX) in human erythrocytes. Blood 57: 209-217, 1981. 2. Morelli, A., De Flora, A. Isolation and partial characterization of an NADP- and NADPH-binding protein from human erythrocytes. Arch. Biochem. Biophys. 179: 698-705, 1977. 3. Smith, P. L., Myers, J. T., Rogers, C. E., Zhou, L., Petryniak, B., Becker, D. J., Homeister, J. W., Lowe, J. B. Conditional control of selectin ligand expression and global fucosylation events in mice with a targeted mutation at the FX locus. J. Cell. Biol. 158: 801-815, 2002.

Uniprot ID: Q13630

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 39 kDa

Calculated Molecular Weight:

Gene ID: 7264

Protein Name: GDP-L-fucose synthase

Gene Full Name: GDP-L-fucose synthase

Synonyms: SDR4E1; TSTA3; GFUS; Protein FX; GDP-L-fucose synthase; P35B