Anti-TPI1 Antibody Picoband®

SKU: A02559-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,Flow Cytometry,WB

Application Details: Western blot, 0.1-0.25 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: TPI1

Specificity:

Background: Triosephosphate isomerase is an enzyme that in humans is encoded by the TPI1 gene. This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants.

Immunogen: E.coli-derived human TPI1 recombinant protein (Position: M1-Q286).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Arya, R., Lalloz, M. R. A., Bellingham, A. J., Layton, D. M. Evidence for founder effect of the glu104-to-asp substitution and identification of new mutations in triosephosphate isomerase deficiency. Hum. Mutat. 10: 290-294, 1997. 2. Asakawa, J., Iida, S. Origin of human triosephosphate isomerase isozymes: further evidence for the single structural locus hypothesis with Japanese variants. Hum. Genet. 71: 22-26, 1985. 3. Asakawa, J., Satoh, C., Takahashi, N., Fujita, M., Kaneko, J., Goriki, K., Hazama, R., Kageoka, T. Electrophoretic variants of blood proteins in Japanese: III. Triosephosphate isomerase. Hum. Genet. 68: 185-188, 1984.

Uniprot ID: P60174

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 27 kDa

Calculated Molecular Weight:

Gene ID: 7167

Protein Name: Triosephosphate isomerase

Gene Full Name: triosephosphate isomerase 1

Synonyms: TIM; TPI; TPI1; Triose phosphate isomerase; Triosephosphate isomerase; triosephosphate isomerase 1