Anti-TNIP1 Antibody Picoband®

SKU: A02299-2

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5μg/ml, -

Gene Name: TNIP1

Specificity:

Background: TNFAIP3-interacting protein 1 is a protein that in humans is encoded by the TNIP1 gene. This gene encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Mutations in this gene have been associated with psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human TNIP1 recombinant protein (Position: E312-K371).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. El Bakkouri, K., Wullaert, A., Haegman, M., Heyninck, K., Beyaert, R. Adenoviral gene transfer of the NK-kappa-B inhibitory protein ABIN-1 decreases allergic airway inflammation in a murine asthma model. J. Biol. Chem. 280: 17938-17944, 2005. 2. Fukushi, M., Dixon, J., Kimura, T., Tsurutani, N., Dixon, M. J., Yamamoto, N. Identification and cloning of a novel cellular protein Naf1, Nef-associated factor 1, that increases cell surface CD4 expression. FEBS Lett. 442: 83-88, 1999. 3. Oshima, S., Turer, E. E., Callahan, J. A., Chai, S., Advincula, R., Barrera, J., Shifrin, N., Lee, B., Yen, B., Woo, T., Malynn, B. A., Ma, A. ABIN-1 is a ubiquitin sensor that restricts cell death and sustains embryonic development. Nature 457: 906-909, 2009. Note: Erratum: Nature 458: 538 only, 2009.

Uniprot ID: Q15025

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 80-85 kDa

Calculated Molecular Weight: 30392 MW

Gene ID: 10318

Protein Name: TNFAIP3-interacting protein 1

Gene Full Name: TNFAIP3 interacting protein 1

Synonyms: ABIN 1; ABIN1; ABIN-1; HIV 1 Nef interacting protein; hVAN; KIAA0113; NAF1; Nef associated factor 1; Nip40 1; TNFAIP3 interacting protein 1; TNIP1; VAN