Anti-STPG2 Antibody Picoband®

SKU: A19412

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: STPG2

Specificity:

Background: STPG2 (sperm tail PG rich repeat containing 2) is a 459 amino acid protein that contains 9 STPGR (sperm-tail PG-rich) repeats in human, and a 561 amino acid protein containing 10 STPGR (sperm-tail PG-rich) repeats in mouse. The gene encoding STPG2 maps to human chromosome 4q22.3 and mouse chromosome 3 H1. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington’s disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes.

Immunogen: E.coli-derived human STPG2 recombinant protein (Position: N39-D399).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Yakut, S. , Cetin, Z. , Clark, O. A. , Usta, M. F. , Berker, S. , & Luleci, G. . (2013). Exceptional complex chromosomal rearrangement and microdeletions at the 4q22.3q23 and 14q31.1q31.3 regions in a patient with azoospermia. Gene, 512(1), 157-160. 2. Jing, J. , Fridley, B. L. , Feng, Q. , Abo, R. P. , Abra, B. , & Anthony, B. , et al. (2013). Genome-wide association study for biomarker identification of rapamycin and everolimus using a lymphoblastoid cell line system. Frontiers in Genetics, 4, 166-166. 3. Lamesch, P. , Li, N. , Milstein, S. , Fan, C. , & Tong, H. . (2007). Horfeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics, 89( 3), 307-315.

Uniprot ID: Q8N412

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 51 kDa

Calculated Molecular Weight: 24145 MW

Gene ID: 285555

Protein Name: Sperm-tail PG-rich repeat-containing protein 2

Gene Full Name: sperm tail PG-rich repeat containing 2

Synonyms: STPG2; C4orf37; Sperm-tail PG-rich repeat-containing protein 2