Anti-SLC25A25 Antibody Picoband®

SKU: A09109-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SLC25A25

Specificity:

Background: The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene.

Immunogen: E.coli-derived human SLC25A25 recombinant protein (Position: M1-R437). Human SLC25A25 shares 97.3% and 96.8% amino acid (aa) sequence identity with mouse and rat SLC25A25, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. del Arco, A., Satrustegui, J. Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains. J. Biol. Chem. 279: 24701-24713, 2004. 2. Mashima, H., Ueda, N., Ohno, H., Suzuki, J., Ohnishi, H., Yasuda, H., Tsuchida, T., Kanamaru, C., Makita, N., Iiri, T., Omata, M., Kojima, I. A novel mitochondrial Ca(2+)-dependent solute carrier in the liver identified by mRNA differential display. J. Biol. Chem. 278: 9520-9527, 2003. 3. Nagase, T., Kikuno, R., Ohara, O. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. DNA Res. 8: 179-187, 2001.

Uniprot ID: Q6KCM7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 50-55 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 114789

Protein Name: Mitochondrial adenyl nucleotide antiporter SLC25A25

Gene Full Name: solute carrier family 25 member 25

Synonyms: APC3; KIAA1896; MCSC; MCSC3; PCSCL; RP11 395P17.4; SCAMC 2; SCAMC2; SLC25A25