Anti-SERPINB13 Antibody Picoband®

SKU: A09602-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SERPINB13

Specificity:

Background: Serpin B13 is a protein that in humans is encoded by the SERPINB13 gene. The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein inhibits the activity of cathepsin K and is itself transcriptionally repressed by RUNX1. This gene is downregulated in many types of cancer.

Immunogen: E.coli-derived human SERPINB13 recombinant protein (Position: M1-H368).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Abts, H. F., Breuhahn, K., Michel, G., Kohrer, K., Esser, P., Ruzicka, T. Analysis of UVB modulated gene expression in human keratinocytes by mRNA differential display polymerase chain reaction. Photochem. Photobiol. 66: 363-367, 1997. 2. Abts, H. F., Welss, T., Mirmohammadsadegh, A., Kohrer, K., Michel, G., Ruzicka, T. Cloning and characterization of hurpin (protease inhibitor 13): a new skin-specific, UV-repressible serine proteinase inhibitor of the ovalbumin serpin family. J. Molec. Biol. 293: 29-39, 1999. 3. Nakashima, T., Pak, S. C., Silverman, G. A., Spring, P. M., Frederick, M. J., Clayman, G. L. Genomic cloning, mapping, structure and promoter analysis of HEADPIN, a serpin which is down-regulated in head and neck cancer cells. Biochim. Biophys. Acta 1492: 441-446, 2000.

Uniprot ID: Q9UIV8

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 44 kDa

Calculated Molecular Weight:

Gene ID: 5275

Protein Name: Serpin B13

Gene Full Name: serpin family B member 13

Synonyms: SERPINB13; PI13; Serpin B13; HaCaT UV-repressible serpin; Hurpin; Headpin; Peptidase inhibitor 13; PI-13; Proteinase inhibitor 13; HUR7; HSHUR7SEQ; serpin family B member 13