Anti-SARS-CoV-2 Spike RBD (CB6 biosimilar) Neutralizing Antibody

SKU: E-AB-V1028

Size::100μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Virus Antibodies

Abbreviation:

Target Synonym:coronavirus s1;coronavirus s2;coronavirus spike;cov spike;ncov RBD;ncov s1;ncov s2;ncov spike;novel coronavirus RBD;novel coronavirus s1;novel coronavirus s2;novel coronavirus spike;RBD;S1;s2;Spike RBD

Research Areas:

Conjugation:Unconjugated

Host:Human

Species reactivity:SARS-COV2

Application:Neutralization;ELISA

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:CB6

UNIProt ID:

Accession:

Background:Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.  

Concentration:0.79 mg/mL

Immunogen:

Buffer:PBS, pH 7.4, 10% glycerol

Purification method:

Dilution:ELISA 1:1000-1:2000

Calculated MW:

ObservedMW: