Anti-RSK3/RPS6KA2 Antibody Picoband®

SKU: A06142-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,IF,IHC,ICC,WB

Application Details: Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml
Immunocytochemistry/Immunofluorescence, 2μg/ml
ELISA, 0.1-0.5μg/ml

Gene Name: RPS6KA2

Specificity: No cross reactivity with other proteins.

Background: Ribosomal protein S6 kinase alpha-2 is an enzyme that in humans is encoded by the RPS6KA2 gene. It is mapped to 6q27. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains two non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternative splice variants, encoding different isoforms, have been characterized.

Immunogen: E. coli-derived human RSK3 recombinant protein (Position: H658-L733).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Zeniou, M., Ding, T., Trivier, E., Hanauer, A. Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning. Hum. Molec. Genet. 11: 2929-2940, 2002. 2. Zhao, Y., Bjorbaek, C., Weremowicz, S., Morton, C. C., Moller, D. E. RSK3 encodes a novel pp90rsk isoform with a unique N-terminal sequence: growth factor-stimulated kinase function and nuclear translocation. Molec. Cell. Biol. 15: 4353-4363, 1995.

Uniprot ID: Q15349

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 90-100 kDa

Calculated Molecular Weight:

Gene ID: 6196

Protein Name: Ribosomal protein S6 kinase alpha-2

Gene Full Name: ribosomal protein S6 kinase A2

Synonyms: HU 2; MAPKAP kinase 1c; MAPKAPK 1c; MAPKAPK1C; p90 RSK 2; p90 RSK3; p90RSK2; pp90RSK3; Ribosomal S6 kinase 3; RPS6KA2; RSK; RSK 3; RSK3; S6K alpha; S6K alpha 2; S6K alpha2