Anti-RERE Antibody Picoband®

SKU: A07605-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: RERE

Specificity:

Background: Arginine-glutamic acid dipeptide repeats protein is a protein that in humans is encoded by the RERE gene. This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human RERE recombinant protein (Position: D109-H1037). Human RERE shares 92.4% and 92.3% amino acid (aa) sequence identity with mouse and rat RERE, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Amler, L. C., Bauer, A., Corvi, R., Dihlmann, S., Praml, C., Cavenee, W. K., Schwab, M., Hampton, G. M. Identification and characterization of novel genes located at the t(1;15)(p36.2;q24) translocation breakpoint in the neuroblastoma cell line NGP. Genomics 64: 195-202, 2000. 2. Bosch, D. G. M., Boonstra, F. N., de Leeuw, N., Pfundt, R., Nillesen, W. M., de Ligt, J., Gilissen, C., Jhangiani, S., Lupski, J. R., Cremers, F. P. M., de Vries, B. B. A. Novel genetic causes for cerebral visual impairment. Europ. J. Hum. Genet. 24: 660-665, 2016. 3. Fregeau, B., Kim, B. J., Hernandez-Garcia, A., Jordan, V. K., Cho, M. T., Schnur, R. E., Monaghan, K. G., Juusola, J., Rosenfeld, J. A., Bhoj, E., Zackai, E. H., Sacharow, S., and 14 others. De novo mutations of RERE cause a genetic syndrome with features that overlap those associated with proximal 1p36 deletions. Am. J. Hum. Genet. 98: 963-970, 2016.

Uniprot ID: Q9P2R6

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 170,212 kDa

Calculated Molecular Weight: 172,109 kDa

Gene ID: 473

Protein Name: Arginine-glutamic acid dipeptide repeats protein

Gene Full Name: arginine-glutamic acid dipeptide repeats

Synonyms: RERE; ARG; ARP; ATN1L; KIAA0458; Arginine-glutamic acid dipeptide repeats protein; Atrophin-1-like protein; Atrophin-1-related protein