Anti-RASSF7 Antibody Picoband®

SKU: A09402-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: RASSF7

Specificity:

Background: RASSF7 (Ras association domain-containing protein 7), also designated HRAS1-related cluster protein 1, is a 373 amino acid protein that localizes to the centrosome. RASSF7, RASSF8, RASSF9 and RASSF10 are four evolutionary conserved proteins that are collectively known as the N-terminal RASSF family. Expressed in skin, neural tube and eye, RASSF7 is believed to play an essential role in mitosis. Further supporting its mitotic role, knockdown of Xenopus RASSF7 has been shown to influence cell failure to form mitotic spindle and also cause nuclear breakdown and apoptosis.

Immunogen: E.coli-derived human RASSF7 recombinant protein (Position: R58-R342). Human RASSF7 shares 77.5% amino acid (aa) sequence identity with mouse RASSF7.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Sherwood, V., Manbodh, R., Sheppard, C., Chalmers, A. D. RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis. Molec. Biol. Cell 19: 1772-1782, 2008. 2. Weitzel, J. N., Kasperczyk, A., Mohan, C., Krontiris, T. G. The HRAS1 gene cluster: two upstream regions recognizing transcripts and a third encoding a gene with a leucine zipper domain. Genomics 14: 309-319, 1992.

Uniprot ID: Q02833

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 37 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 8045

Protein Name: Ras association domain-containing protein 7

Gene Full Name: Ras association domain family member 7

Synonyms: RASSF7; C11orf13; HRC1; Ras association domain-containing protein 7; HRAS1-related cluster protein 1