Anti-RAB1A Antibody Picoband®

SKU: A02682-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: RAB1A

Specificity:

Background: Ras-related protein Rab-1A is a protein that in humans is encoded by the RAB1A gene. This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms.

Immunogen: E.coli-derived human RAB1A recombinant protein (Position: R74-Q199).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Allan, B. B., Moyer, B. D., Balch, W. E. Rab1 recruitment of p115 into a cis-SNARE complex: programming budding COPII vesicles for fusion. Science 289: 444-448, 2000. 2. Cooper, A. A., Gitler, A. D., Cashikar, A., Haynes, C. M., Hill, K. J., Bhullar, B., Liu, K., Xu, K., Strathearn, K. E., Liu, F., Cao, S., Caldwell, K. A., Caldwell, G. A., Marsischky, G., Kolodner, R. D., LaBaer, J., Rochet, J.-C., Bonini, N. M., Lindquist, S. Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science 313: 324-328, 2006. 3. Ingmundson, A., Delprato, A., Lambright, D. G., Roy, C. R. Legionella pneumophila proteins that regulate Rab1 membrane cycling. Nature 450: 365-369, 2007.

Uniprot ID: P62820

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 23,22 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 5861

Protein Name: Ras-related protein Rab-1A

Gene Full Name: RAB1A, member RAS oncogene family

Synonyms: RAB1; RAB1A; Ras related protein Rab 1A; YPT1; YPT1 related protein