Anti-PTPIP51/RMDN3 Antibody Picoband®

SKU: A09297

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,IHC,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: RMDN3

Specificity:

Background: Regulator of microtubule dynamics protein 3 (RMDN3), more commonly known as Protein tyrosine phosphatase interacting protein 51 (PTPIP51), is a protein that in humans is encoded by the RMDN3 gene on chromosome 15. Enables microtubule binding activity. Involved in cellular calcium ion homeostasis. Located in several cellular components, including intercellular bridge; mitochondrial outer membrane; and spindle.

Immunogen: E.coli-derived human PTPIP51/RMDN3 recombinant protein (Position: Q45-R438).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. De Vos, K. J., Morotz, G. M., Stoica, R., Tudor, E. L., Lau, K.-F., Ackerly, S., Warley, A., Shaw, C. E., Miller, C. C. J. VAPB interacts with the mitochondrial protein PTPIP51 to regulate calcium homeostasis. Hum. Molec. Genet. 21: 1299-1311, 2012. 2. Lv, B. F., Yu, C. F., Chen, Y. Y., Lu, Y., Guo, J. H., Song, Q. S., Ma, D. L., Shi, T. P., Wang, L. Protein tyrosine phosphatase interacting protein 51 (PTPIP51) is a novel mitochondria protein with an N-terminal mitochondrial targeting sequence and induces apoptosis. Apoptosis 11: 1489-1501, 2006. 3. Oishi, K., Okano, H., Sawa H. RMD-1, a novel microtubule-associated protein, functions in chromosome segregation in Caenorhabditis elegans. J. Cell Biol. 179: 1149-1162, 2007. Note: Erratum: J. Cell Biol. 186: 629 only, 2009.

Uniprot ID: Q96TC7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 55 kDa

Calculated Molecular Weight:

Gene ID: 55177

Protein Name: Regulator of microtubule dynamics protein 3

Gene Full Name: regulator of microtubule dynamics 3

Synonyms: FAM82A2; FAM82C; hRMD 3; Protein FAM82A2; Protein FAM82C; PTPIP51; RMD 3; RMD3