Anti-Prostaglandin E Receptor EP2/PTGER2 Antibody Picoband®

SKU: PB9386

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: WB

Application Details: Western blot, 0.1-0.5μg/ml, Human

Gene Name: PTGER2

Specificity: No cross reactivity with other proteins.

Background: Prostaglandin E2 receptor (53kDa), also known as EP2, is aprostaglandin receptor for prostaglandin E2. It is encoded by the human gene PTGER2. It may be associated with aspirin-induced asthma. PTGER2 is mapped to chromosome 14q22. This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human PTGER2, different from the related mouse sequence by four amino acids, and from the related rat sequence by three amino acids.

Clonality: Polyclonal

Contents: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg NaN3.
*This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Smock, S. L., Pan, L. C., Castleberry, T. A., Lu, B., Mather, R. J., Owen, T. A. Cloning, structural characterization, and chromosomal localization of the gene encoding the human prostaglandin E2 receptor EP2 subtype. Gene 237: 393-402, 1999. 2. Sugimoto Y, Nakato T, Kita A et al. (2004). A cluster of aromatic amino acids in the i2 loop plays a key role for Gs coupling in prostaglandin EP2 and EP3 receptors. J. Biol. Chem. 279 (12): 11016–26.

Uniprot ID: P43116

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 40 kDa

Calculated Molecular Weight: 39761 MW

Gene ID: 5732

Protein Name: Prostaglandin E2 receptor EP2 subtype

Gene Full Name: prostaglandin E receptor 2

Synonyms: prostaglandin E receptor 2; EP2; PTGER2