Anti-PRDM5 Antibody Picoband®

SKU: A06736-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.1-0.25μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2μg/ml, Human
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: PRDM5

Specificity: No cross reactivity with other proteins.

Background: PR domain zinc finger protein 5 is a protein that in humans is encoded by the PRDM5 gene. It is mapped to 4q27. The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis.

Immunogen: E.coli-derived human PRDM5 recombinant protein (Position: Y24-S630).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Aldahmesh, M. A., Mohamed, J. Y., Alkuraya, F. S. A novel mutation in PRDM5 in brittle cornea syndrome. (Letter) Clin. Genet. 81: 198-199, 2012. 2. Burkitt Wright, E. M. M., Spencer, H. L., Daly, S. B., Manson, F. D. C., Zeef, L. A. H., Urquhart, J., Zoppi, N., Bonshek, R., Tosounidis, I., Mohan, M., Madden, C., Dodds, A., and 11 others. Mutations in PRDM5 in brittle cornea syndrome identify a pathway regulating extracellular matrix development and maintenance. Am. J. Hum. Genet. 88: 767-777, 2011. Note: Erratum: Am. J. Hum. Genet. 89: 346 only, 2011. 3. Deng, Q., Huang, S. PRDM5 is silenced in human cancers and has growth suppressive activities. Oncogene 23: 4903-4910, 2004.

Uniprot ID: Q9NQX1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 75 kDa

Calculated Molecular Weight: 104553 MW

Gene ID: 11107

Protein Name: PR domain zinc finger protein 5

Gene Full Name: PR/SET domain 5

Synonyms: PFM2; PR domain containing 5; PR domain containing protein 5; PRDM5