Anti-PNPLA1 Antibody Picoband®

SKU: A09557-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: PNPLA1

Specificity:

Background: PNPLA1 is important in the formation of the epidermal lipid barrier and plays a role in glycerophospholipid metabolism.

Immunogen: E.coli-derived human PNPLA1 recombinant protein (Position: K141-D496). Human PNPLA1 shares 51.5% amino acid (aa) sequence identity with mouse PNPLA1.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Ahmad, F., Ansar, M., Mehmood, S., Izoduwa, A., Lee, K., Nasir, A., Abrar, M., Mehmood, S., Ullah, A., Aziz, A., University of Washington Center for Mendelian Genomics, Smith, J. D., Shendure, J., Bamshad, M. J., Nicekrson, D. A., Santos-Cortez, R. L. P., Leal, S. M., Ahmad, W. A novel missense variant in the PNPLA1 gene underlies congenital ichthyosis in three consanguineous families. J. Europ. Acad. Derm. Venereol. 30: e210-e213, 2016. Note: Electronic Article. 2. Boyden, L. M., Craiglow, B. G., Hu, R. H., Zhou, J., Browning, J., Eishenfield, L., Lim, Y. L., Luu, M., Randolph, L. M., Ginarte, M., Fachal, L., Rodriguez-Pazos, L., and 10 others. Phenotypic spectrum of autosomal recessive congenital ichthyosis due to PNPLA1 mutation. Brit. J. Derm. 177: 319-322, 2017. 3. Fachal, L., Rodriguez-Pazos, L., Ginarte, M., Carracedo, A., Toribio, J., Vega, A. Identification of a novel PNPLA1 mutation in a Spanish family with autosomal recessive congenital ichthyosis. (Letter) Brit. J. Derm. 170: 980-982, 2014.

Uniprot ID: Q8N8W4

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 58 kDa

Calculated Molecular Weight:

Gene ID: 285848

Protein Name: Omega-hydroxyceramide transacylase

Gene Full Name: patatin like domain 1, omega-hydroxyceramide transacylase

Synonyms: PNPLA1; Patatin-like phospholipase domain-containing protein 1