Anti-PLA2G6 Antibody Picoband®

SKU: A01648-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,ICC/IF,WB

Application Details: Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: PLA2G6

Specificity: No cross reactivity with other proteins.

Background: 85 kDa calcium-independent phospholipase A2 is an enzyme that in humans is encoded by the PLA2G6 gene. The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.

Immunogen: E. coli-derived human PLA2G6 recombinant protein (Position: W715-L802).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent). 2. Larsson PK, Claesson HE, Kennedy BP (Jan 1998). Multiple splice variants of the human calcium-independent phospholipase A2 and their effect on enzyme activity. The Journal of Biological Chemistry. 273 (1): 207–14. 3. Wilson PA, Gardner SD, Lambie NM, Commans SA, Crowther DJ (Sep 2006). Characterization of the human patatin-like phospholipase family. Journal of Lipid Research. 47 (9): 1940–9.

Uniprot ID: O60733

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 84 kDa

Calculated Molecular Weight: 90 kDa

Gene ID: 8398

Protein Name: 85/88 kDa calcium-independent phospholipase A2

Gene Full Name: phospholipase A2 group VI

Synonyms: CaI PLA2; Group VI phospholipase A2; GVI; GVI PLA2; INAD1; iPLA2; iPLA2 beta; IPLA2 VIA; PARK14; PLA2; PLA2G6; PNPLA9