Anti-PAN3 Antibody Picoband®

SKU: A05429-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse

Applications: WB,IHC,ICC/IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: PAN3

Specificity:

Background: Contributes to poly(A)-specific ribonuclease activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within deadenylation-dependent decapping of nuclear-transcribed mRNA; positive regulation of cytoplasmic mRNA processing body assembly; and protein targeting. Part of PAN complex.

Immunogen: E.coli-derived human PAN3 recombinant protein (Position: Q227-L887). Human PAN3 shares 97.4% amino acid (aa) sequence identity with mouse PAN3.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Hartz, P. A. Personal Communication. Baltimore, Md. 04/21/2017. 2. Uchida, N., Hoshino, S., Katada, T. Identification of a human cytoplasmic poly(A) nuclease complex stimulated by poly(A)-binding protein. J. Biol. Chem. 279: 1383-1391, 2004.

Uniprot ID: Q58A45

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 96 kDa

Calculated Molecular Weight: 96 kDa

Gene ID: 255967

Protein Name: PAN2-PAN3 deadenylation complex subunit PAN3

Gene Full Name: poly(A) specific ribonuclease subunit PAN3

Synonyms: Poly(A)-nuclease deadenylation complex subunit 3; PAN2-PAN3 deadenylation complex subunit PAN3; PAN deadenylation complex subunit 3; PAB1P-dependent poly(A)-specific ribonuclease; hPan3