Anti-OAT3/SLC22A8 Antibody Picoband®

SKU: A04087-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: ELISA,Flow Cytometry,IF,IHC,WB

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SLC22A8

Specificity:

Background: Solute carrier family 22 member 8, or organic anion transporter 3 (OAT3), is a protein that in humans is encoded by the SLC22A8 gene. This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Immunogen: E.coli-derived human OAT3/SLC22A8 recombinant protein (Position: M1-Q470).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Race, J. E., Grassl, S. M., Williams, W. J., Holtzman, E. J. Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3). Biochem. Biophys. Res. Commun. 255: 508-514, 1999. 2. Sun, W., Wu, R. R., van Poelje, P. D., Erion, M. D. Isolation of a family of organic anion transporters from human liver and kidney. Biochem. Biophys. Res. Commun. 283: 417-422, 2001.

Uniprot ID: Q8TCC7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 62 kDa

Calculated Molecular Weight: 211344 MW

Gene ID: 9376

Protein Name: Organic anion transporter 3

Gene Full Name: solute carrier family 22 member 8

Synonyms: SLC22A8; OAT3; Solute carrier family 22 member 8; Organic anion transporter 3; hOAT3