Anti-NUDT6 Antibody Picoband®

SKU: A08301-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse
ELISA, 0.1-0.5 μg/ml, -

Gene Name: NUDT6

Specificity:

Background: Nucleoside diphosphate-linked moiety X motif 6 is a protein that in humans is encoded by the NUDT6 gene. This gene overlaps and lies on the opposite strand from FGF2 gene, and is thought to be the FGF2 antisense gene. The two genes are independently transcribed, and their expression shows an inverse relationship, suggesting that this antisense transcript may regulate FGF2 expression. This gene has also been shown to have hormone-regulatory and antiproliferative actions in the pituitary that are independent of FGF2 expression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human NUDT6 recombinant protein (Position: D45-K303).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Asa, S. L., Ramyar, L., Murphy, P. R., Li, A. W., Ezzat, S. The endogenous fibroblast growth factor-2 antisense gene product regulates pituitary cell growth and hormone production. Molec. Endocr. 15: 589-599, 2001. 2. Gagnon, M. L., Moy, G. K., Klagsbrun, M. Characterization of the promoter for the human antisense fibroblast growth factor-2 gene; regulation by Ets in Jurkat T cells. J. Cell. Biochem. 72: 492-506, 1999. 3. Murphy, P. R., Knee, R. S. Identification and characterization of an antisense RNA transcript (gfg) from the human basic fibroblast growth factor gene. Molec. Endocr. 8: 852-859, 1994.

Uniprot ID: P53370

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 72 kDa

Calculated Molecular Weight:

Gene ID: 11162

Protein Name: Nucleoside diphosphate-linked moiety X motif 6

Gene Full Name: nudix hydrolase 6

Synonyms: ASFGF2; FGF AS; FGF2AS; gfg; gfg 1; Nudix motif 6; NUDT6; Protein GFG