Anti-NUDT19 Antibody Picoband®

SKU: A14864-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Rat

Applications: WB,IHC,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/ml, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: NUDT19

Specificity:

Background: NUDT19 (nudix (nucleoside diphosphate linked moiety X)-type motif 19), also known as RP2, is a 375 amino acid protein and coenzyme A diphosphatase that assists in the hydrolysis of CoA esters. A member of the nudix hydrolase family, NUDT19 contains one nudix hydrolase domain and localizes to both mitochondria and peroxisome. NUDT19 utilizes magnesium and/or manganese as cofactors and is encoded by a gene that maps to human chromosome 19q13.11. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.

Immunogen: E.coli-derived human NUDT19 recombinant protein (Position: H52-L375). Human NUDT19 shares 66.4% and 65.8% amino acid (aa) sequence identity with mouse and rat NUDT19, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Lan, C., Wang, Y., Su, X., Lu, J., & Ma, S. (2021). LncRNA LINC00958 activates mTORC1/P70S6K signalling pathway to promote epithelial-mesenchymal transition process in the hepatocellular carcinoma. Cancer Investigation, 39(6-7), 539-549. 2. Ofman, R., Speijer, D., Leen, R., & Wanders, R. J. (2006). Proteomic analysis of mouse kidney peroxisomes: identification of RP2p as a peroxisomal nudix hydrolase with acyl-CoA diphosphatase activity. Biochemical Journal, 393(2), 537-543. 3. Gendep Investigators, Mars Investigators, & Star* D Investigators. (2013). Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies. American Journal of Psychiatry, 170(2), 207-217.

Uniprot ID: A8MXV4

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 40 kDa

Calculated Molecular Weight:

Gene ID: 390916

Protein Name: Acyl-coenzyme A diphosphatase NUDT19

Gene Full Name: nudix hydrolase 19

Synonyms: NUDT19; RP2; Nudix motif 19