Anti-Nms Antibody

SKU: A15072-3

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: IHC,ELISA

Application Details: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: Nms

Specificity:

Background: Neuromedin S is a 36-amino acid neuropeptide found in the brain of humans and other mammals. This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in the regulation of circadian rhythm, anorexigenic action, antidiuretic action, cardiovascular function and stimulation of oxytocin and vasopressin release. Mice lacking the encoded neuropeptide exhibit decreased heart rate without any accompanying changes in blood pressure. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate the mature peptide.

Immunogen: E.coli-derived mouse Nms recombinant protein (Position: D36-N144).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Miyazato, M., Mori, K., Ida, T., Kojima, M., Murakami, N., Kangawa, K. Identification and functional analysis of a novel ligand for G protein-coupled receptor, neuromedin S. Regul. Pept. 145: 37-41, 2008. 2. Mori, K., Miyazato, M., Ida, T., Murakami, N., Serino, R., Ueta, Y., Kojima, M., Kangawa, K. Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J. 24: 325-335, 2005. 3. Sakamoto, T., Nakahara, K., Maruyama, K., Katayama, T., Mori, K., Miyazato, M., Kangawa, K., Murakami, N. Neuromedin S regulates cardiovascular function through the sympathetic nervous system in mice. Peptides 32: 1020-1026, 2011.

Uniprot ID: Q5H8A1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 150 kDa

Calculated Molecular Weight: 19908 MW

Gene ID: 433292

Protein Name: Neuromedin-S

Gene Full Name: neuromedin S

Synonyms: Nms; Neuromedin-S