Anti-NLRP9 Antibody Picoband®

SKU: A14119-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: NLRP9

Specificity:

Background: The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5.

Immunogen: E.coli-derived human NLRP9 recombinant protein (Position: H118-H746).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Inohara, N., Nunez, G. NODs: intracellular proteins involved in inflammation and apoptosis. Nature Rev. Immun. 3: 371-382, 2003. 2. Tschopp, J., Martinon, F., Burns, K. NALPs: a novel protein family involved in inflammation. Nature Rev. Molec. Cell Biol. 4: 95-104, 2003. 3. Zhu, S., Ding, S., Wang, P., Wei, Z., Pan, W., Palm, N. W., Yang, Y., Yu, H., Li, H.-B., Wang, G., Lei, X., de Zoete, M. R., and 13 others. Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. Nature 546: 667-670, 2017.

Uniprot ID: Q7RTR0

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 113 kDa

Calculated Molecular Weight: 64099 MW

Gene ID: 338321

Protein Name: NACHT, LRR and PYD domains-containing protein 9

Gene Full Name: NLR family pyrin domain containing 9

Synonyms: NLRP9; NALP9; NOD6; PAN12; NACHT, LRR and PYD domains-containing protein 9; Nucleotide-binding oligomerization domain protein 6; PYRIN and NACHT-containing protein 12