Anti-NEUROG1 Antibody Picoband®

SKU: A05933-2

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human

Gene Name: NEUROG1

Specificity:

Background: Enables E-box binding activity and protein homodimerization activity. Involved in several processes, including cochlea morphogenesis; cranial nerve development; and hard palate morphogenesis. Predicted to be located in chromatin. Predicted to be active in nucleus.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human NEUROG1. Human NEUROG1 shares 93.8% amino acid (aa) sequence identity with both mouse and rat NEUROG1.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Dupont, J., Vieira, J. P., Tavares, A. L. T., Conceicao, C. R., Khan, S., Bertoli-Avella, A. M., Sousa, A. B. Adding evidence to the role of NEUROG1 in congenital cranial dysinnervation disorders. Clin. Genet. 99: 588-593, 2021. 2. Gowan, K., Helms, A. W., Hunsaker, T. L., Collisson, T., Ebert, P. J., Odom, R., Johnson, J. E. Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons. Neuron 31: 219-232, 2001. 3. Lee, J. E., Hollenberg, S. M., Snider, L., Turner, D. L., Lipnick, N., Weintraub, H. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 268: 836-844, 1995.

Uniprot ID: Q92886

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 26 kDa

Calculated Molecular Weight: 26 kDa

Gene ID: 4762

Protein Name: Neurogenin-1

Gene Full Name: neurogenin 1

Synonyms: NEUROD3; Math4C; Class A basic helix-loop-helix protein 6; bHLHa6; AKA