Anti-NAGA Antibody Picoband®

SKU: A04163-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/ml

Gene Name: NAGA

Specificity:

Background: NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease).

Immunogen: E.coli-derived human NAGA recombinant protein (Position: D43-R329). Human NAGAshares 86.7% and 85.4% amino acid (aa) sequence identity with mouse and rat NAGA, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Bakker, H. D., de Sonnaville, M.-L. C. S., Vreken, P., Abeling, N. G. G. M., Groener, J. E. M., Keulemans, J. L. M., van Diggelen, O. P. Human alpha-N-acetylgalactosaminidase (alpha-NAGA) deficiency: no association with neuroaxonal dystrophy? Europ. J. Hum. Genet. 9: 91-96, 2001. 2. Chabas, A., Coll, M. J., Aparicio, M., Rodriguez Diaz, E. Mild phenotypic expression of alpha-N-acetylgalactosaminidase deficiency in two adult siblings. J. Inherit. Metab. Dis. 17: 724-731, 1994. 3. de Groot, P. G., Westerveld, A., Meera Khan, P., Tager, J. M. Localization of a gene for human alpha-galactosidase B (=N-acetyl-alpha-D-galactosaminidase) on chromosome 22. Hum. Genet. 44: 305-312, 1978.

Uniprot ID: P17050

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 60 kDa

Calculated Molecular Weight: 47 kDa

Gene ID: 4668

Protein Name: Alpha-N-acetylgalactosaminidase

Gene Full Name: alpha-N-acetylgalactosaminidase

Synonyms: Alpha galactosidase B; D22S674; GALB; NAGA