Anti-L1TD1 Antibody Picoband®

SKU: A12503-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: L1TD1

Specificity:

Background: L1TD1 is an RNA-binding protein highly and specifically expressed in pluripotent cells. It is essential for maintaining the pluripotentency in human embryonic stem cells(hESCs) and has been considered as a markerfor undifferentiated hESCs. L1TD1 is also reported to be highly expressed in medulloblastoma cells and its expression in medulloblastoma correlates with poor clinical outcome.

Immunogen: E.coli-derived human L1TD1 recombinant protein (Position: D34-H852).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Casarotto, M. , Lupato, V. , Giurato, G. , Guerrieri, R. , Sulfaro, S. , & Salvati, A. , et al. (2022). Line-1 hypomethylation is associated with poor outcomes in locoregionally advanced oropharyngeal cancer. Clinical Epigenetics, 14(1), 1-13. 2. Mckerrow, W. , Wang, X. , Mendez-Dorantes, C. , Mita, P. , Cao, S. , & Grivainis, M. . (2022). Line-1 expression in cancer correlates with p53 mutation, copy number alteration, and s phase checkpoint. Proceedings of the National Academy of Sciences of the United States of America.(8), 119.

Uniprot ID: Q5T7N2

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 120 kDa

Calculated Molecular Weight:

Gene ID: 54596

Protein Name: LINE-1 type transposase domain-containing protein 1

Gene Full Name: LINE1 type transposase domain containing 1

Synonyms: ECAT11; ES cell associated protein 11; L1TD1